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Pharmaceutical Technology Cold Storage Project

Shanghai Zhici Medical upgraded its 160m³ pharmaceutical cold storage network, focusing on enhancing reliability of two 20m³ core units to meet stringent global standards for vaccine and biological st

Project Overview

Achieve 99.99% system availability through redundancy design, ensure full-temperature-range compliance (-20°C to 8°C), and realize 100% electronic audit trail.

Start time 2020

Industry Medicine

Project location Shanghai

Total Cold Storage Capacity 160 m³

Temperature Range 2°C–8°C

Humidity Control 35%–75% RH

Sensor Accuracy ±0.1°C，±1.5% RH

Alarm Response Time ≤15 seconds

Control System PLC+SCADA

Challenges Faced

Temperature Uniformity

Maintaining ±1°C consistency across 160m³ space required breakthroughs in sensor density and control algorithms.

Cost-Benefit Balance

Full redundancy design increased initial investment by 40%, demanding rigorous ROI justification.

Regulatory Harmonization

Reconciling differences in data integrity, alarm prioritization, and calibration cycles across Chinese, European, and U.S. GMP standards.

XNAIR Cold Storage Solution

Hierarchical Control Architecture

Deployed "master PLC + zone slave" system with 12 high-density sensor nodes per 20m³ unit, enabling 0.5m-resolution grid monitoring.

Dynamic Redundancy Strategy (动态冗余策略)

Implemented N+1 compressor configuration with load-prediction algorithms, reducing backup unit activation time by 60%.

Compliance Mapping Tool (合规映射工具)

Developed automated documentation generator aligning with three regulatory frameworks, cutting manual verification work by 70%.

Project Results and Benefits

Reliability Improvement

MTBF increased from 8,000 to 24,000 hours; fault handover time reduced to 8 seconds.

Energy Optimization

Annual power consumption reduced by 280,000 kWh through variable-frequency drives and heat recovery, equivalent to 234 tons CO₂ reduction.

Audit Efficiency

100% electronic records compliance enabled 60% faster FDA inspections and zero-defect EMA remote audits.

Achieved industry-leading 99.99% uptime through hybrid redundancy architecture and AI-driven predictive maintenance.

The 160m³ cold chain network now operates like a Swiss watch. We've eliminated manual data reconciliation and reduced batch release time by 40%. —— Manager

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Pharmaceutical Technology Cold Storage Project

Project Overview

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